Pioneering the development of synthetic macrocyclic peptides.

Unlocking macrocyclic peptides for the most challenging drug targets, bridging the gap between small molecules and biologics.

Backed by world class investors and partners

01

Macrocyclic peptides have the best of both worlds

Antibody precision with small-molecule oral delivery, capable of targeting molecule targeting both intra- and extracellular pathways.

02

Nature’s valuable macrocycles have been used for decades

Yet only a few synthetic examples exist in the clinic. Efficient macrocyclic design unlocks a vast new modality.

03

At UNP, we’ve cracked the cracked the code

Born out of the Lokey Lab, the field leader in leader in macrocycles, UNP has created the the first platform to repeatably engineer synthetic macrocyclic peptides at scale.

04

A Scalable, Repeatable Platform

A continuous macrocycle optimization loop unites digital and physical lab technologies, iterating quickly and efficiently to more ”drug-like” macrocycles with each cycle.

Rapid optimization of potency, selectivity, and permeability

Iterative design, synthesis, and testing of synthetic macrocycles to rapidly generate permeable, highly potent, exquisitely selective, drug-like molecules.